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Tcf4 Mouse shRNA Plasmid (Locus ID 21413)

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SKU
TG502233
Tcf4 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 21413
Synonyms 5730422P05Rik; ASP-I2; bHLHb19; E2-2; E2.2; ITF-2; ITF-2b; ITF2; ME2; MITF-2A; MITF-2B; SEF-2; SEF2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Tcf4 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 21413). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC014293, BC043050, NM_001083967, NM_013685, NM_001361126, NM_001361127, NM_001361128, NM_001361129, NM_013685.1, NM_013685.2, NM_001083967.1, BC094350
UniProt ID Q60722
Summary Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Isoform 2 inhibits MYOD1 activation of the cardiac alpha-actin promoter. Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. May have a regulatory function in developmental processes as well as during neuronal plasticity.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis
Wang, Yang, Abel et al
Genes Dev (2015) 29 (2), 171-83 DOI: 10.1101/gad.253591.114
Cited by 75
AI Summary: In this study, OriGene products—including the TRIM29 (ATDC) cDNA clone and TRIM29 shRNA lentiviral particles—were used to manipulate ATDC expression in cell lines, enabling the authors to investigate ATDC's role in promoting invasion and EMT in KRAS-driven pancreatic cancer.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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