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Ddx6 Mouse shRNA Plasmid (Locus ID 13209)

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SKU
TG500516
Ddx6 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 13209
Synonyms 1110001P04Rik; E230023J21Rik; HLR2; mRCK/P54; p54; rck
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Ddx6 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 13209). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC021452, NM_001110826, NM_007841, NM_181324, NM_001357702, NM_001357703, NM_001110826.1, NM_007841.1, NM_007841.2, NM_007841.3, NM_007841.4, NM_181324.1, NM_181324.2, NM_181324.3
UniProt ID P54823
Summary In the process of mRNA degradation, plays a role in mRNA decapping (By similarity). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:26098573).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Phosphorothioate Antisense Oligonucleotides Bind P-Body Proteins and Mediate P-Body Assembly
Wang, Shen, Liang et al
Nucleic Acid Ther (2019)
AI Summary: OriGene’s PCMV6-DDX6-turbo green fluorescent protein (tGFP) plasmid was used in this study to express and visualize DDX6, enabling investigation of its role in P-body assembly and interactions with phosphorothioate antisense oligonucleotides.
Snippet: Plasmid construction and primers. PCMV6-DDX6-turbo green fluorsecent protein (tGFP) plasmid was purchased from Origene. DDX6-tGFP mutants were generated using Site-Directed Mutagenesis Kit (Thermo Fisher) following manufacturer's protocols
Showing 1-1 of 1 papers.
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