Cdkn2a Mouse shRNA Plasmid (Locus ID 12578)
Specifications
| Product Data | |
| Locus ID | 12578 |
|---|---|
| Synonyms | Arf; ARF-INK4a; INK4a-ARF; Ink4a/Arf; MTS1; p16; p16(INK4a); p16INK4a; p19 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Cdkn2a - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 12578). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC058190, NM_001040654, NM_009877, NM_009877.1, NM_009877.2, NM_001040654.1 |
| UniProt ID | Q64364 |
| Summary | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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