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SLK Human shRNA Plasmid Kit (Locus ID 9748)

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SKU
TG320620
SLK - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 9748
Synonyms bA16H23.1; LOSK; se20-9; STK2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components SLK - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 9748). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001304743, NM_014720, NM_014720.1, NM_014720.2, NM_014720.3, BC008697, BC036736, BC047762, BC047885, BC064804, BC111565, NM_014720.4
UniProt ID Q9H2G2
Summary Mediates apoptosis and actin stress fiber dissolution.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Two independent translocation modes drive neural stem cell dissemination into the human fetal cortex
Wimmer, Lestienne, Brunet et al
bioRxiv (2025)
Cited by 5
AI Summary: OriGene products, specifically shRNAs targeting Human EZR (TF308420), STK10 (TF320540), SLK (TG320620), DYNC1H1 (TL313335), RDX (TL309884), MSN (TL311375), ECT2 (TL304854), VIM (TL308419), and PAFAH1B1/LIS1 (TL310628), were used in this study to selectively knock down genes and investigate their roles in the distinct translocation modes of neural stem cells during human cortical development.
Snippet: … Benaroch), Human EZR shRNA (TF308420, Origene), Human STK10 shRNA (TF320540, Origene), Human SLK shRNA (TG320620, Origene), Human DYNC1H1 shRNA (TL313335, Origene), Human RDX shRNA (TL309884, Origene), Human MSN shRNA (TL311375, Origene), Human ECT2 shRNA (TL304854, Origene), Human VIM shRNA (TL308419, Origene), Human PAFAH1B1 (LIS1) shRNA (TL310628, Origene), Dominant Negative KASH. …
SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation
Machicoane, de Frutos, Fink et al
J. Cell Biol. (2014) 205 (6), 791-9 DOI: 10.1083/jcb.201401049
Cited by 104
AI Summary: OriGene products contributed to this study by providing SLK shRNA-encoding plasmids (SLK#1 and SLK#2), which were used to specifically knock down SLK expression and investigate its role in ERM activation and spindle orientation.
Snippet: 1, 2, 4, and S1–S3). Scramble and shRNA-encoding plasmids were purchased from Origene: SLK#1 (5′-GGAGTTAGATGAGGAACATAGCCAAGAAT-3′;Fig. 3) and SLK#2 (5′-GAAGACAGTGCTGAGGATACGCAGAGTAA-3′;Fig. S1). ... Cite SaveSaving
Showing 1-2 of 2 papers.
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