PERK (EIF2AK3) Human shRNA Plasmid Kit (Locus ID 9451)
SKU
TG320616
EIF2AK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 9451 |
|---|---|
| Synonyms | PEK; PERK; WRS |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | EIF2AK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 9451). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001313915, NM_004836, NM_004836.1, NM_004836.2, NM_004836.3, NM_004836.4, NM_004836.5, NM_004836.6, BC040505, BC126354, BC126356, NM_004836.7 |
| UniProt ID | Q9NZJ5 |
| Summary | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. provided by RefSeq, Sep 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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