PKR (EIF2AK2) Human shRNA Plasmid Kit (Locus ID 5610)

SKU
TG320493
EIF2AK2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 5610
Synonyms EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components EIF2AK2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5610). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001135651, NM_001135652, NM_002759, NM_002759.1, NM_002759.2, NM_002759.3, NM_001135651.1, NM_001135651.2, NM_001135652.1, NM_001135652.2, BC093676, BC093676.1, BC007769, BC022314, BC040851, BC057805, BC101475, BC143228, BC143230, BM473760, NM_001135651.3
UniProt ID P19525
Summary The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Oct 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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