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NF2 Human shRNA Plasmid Kit (Locus ID 4771)

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SKU
TG316639
NF2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 4771
Synonyms ACN; BANF; merlin-1; SCH
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components NF2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 4771). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_000268, NM_016418, NM_181825, NM_181826, NM_181827, NM_181828, NM_181829, NM_181830, NM_181831, NM_181832, NM_181833, NM_181834, NM_181835, NM_181830.1, NM_181830.2, NM_000268.1, NM_000268.2, NM_000268.3, NM_181832.1, NM_181832.2, NM_181829.1, NM_181829.2, NM_181833.1, NM_181833.2, NM_016418.3, NM_016418.5, NM_181825.1, NM_181825.2, NM_181828.1, NM_181828.2, NM_181831.1, NM_181831.2, NM_181827.1, BC003112, BC003112.1, BC020257, BC020257.1, BC007279, BC007336, BC010060, BC071653, NR_156186, NM_181825.3, NM_181829.3, NM_181831.3, NM_181830.3, NM_181832.3, NM_181828.3, NM_000268.4
UniProt ID P35240
Summary This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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