BIRC5 Human shRNA Plasmid Kit (Locus ID 332)
SKU
TG315477
BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 332 |
|---|---|
| Synonyms | API4; EPR-1 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 332). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001012270, NM_001012271, NM_001168, NM_001168.1, NM_001168.2, NM_001012270.1, NM_001012271.1, BC034148, BC034148.1, BC000784, BC008718, BC065497, BM476145, NM_001012271.2, NM_001012270.2 |
| UniProt ID | O15392 |
| Summary | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Molecular Chaperone gp96 Is a Novel Therapeutic Target of Multiple Myeloma
Hua, White-Gilbertson, Kellner et al
Clin. Cancer Res. (2013)
Hua, White-Gilbertson, Kellner et al
Clin. Cancer Res. (2013)
AI Summary: OriGene Technologies supplied the survivin retroviral vector and empty vector control, which were used in this study to investigate the role of survivin in multiple myeloma cell growth and survival.
Snippet: Viral vectors and transduction Human gp96 and surivin short hairpin RNA (shRNA) lentiviral vectors as well as control vector were purchased from Open Biosystems. Survivin retroviral vector and empty vector control were obtained from Origene Technologies.
IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin
Botto, Streblow, DeFilippis et al
Blood (2011) 117 (1), 352-61 DOI: 10.1182/blood-2010-06-291245
Botto, Streblow, DeFilippis et al
Blood (2011) 117 (1), 352-61 DOI: 10.1182/blood-2010-06-291245
Cited by 111
AI Summary: OriGene’s HuSH shRNA Plasmid Panels (29-mer) were used in this study to knock down survivin expression in endothelial cells, enabling the researchers to demonstrate survivin’s role in HCMV secretome-induced angiogenesis and cell survival.
Snippet: grown on as ϕNX-A cells described in the HuSH shRNA Plasmid Panels (29-mer) Application Guide (TG315477;OriGene Technology). ... A comparison between the viral and mock secretomes indicated 29 significantly induced and 6 down-regulated factors (Table 1). The most
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
