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APLP2 Human shRNA Plasmid Kit (Locus ID 334)

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SKU
TG314731
APLP2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 334
Synonyms APLP-2; APPH; APPL2; CDEBP
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components APLP2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 334). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC004371, NM_001142276, NM_001142277, NM_001142278, NM_001243299, NM_001642, NR_024515, NR_024516, NM_001328682, NM_001328684, NM_001328685, NM_001328686, NM_001642.1, NM_001642.2, NM_001142276.1, NM_001142277.1, NM_001142278.1, NM_001243299.1, BC004371.1, BC000373, BM992563, NM_001142278.2, NM_001642.3, NM_001142277.2, NM_001142276.2
UniProt ID Q06481
Summary This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Aug 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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