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CREB1 Human shRNA Plasmid Kit (Locus ID 1385)

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SKU
TG313740
CREB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Other products for "CREB1 or NM_004379"

Specifications
Specifications
Product Data
Locus ID 1385
Synonyms CREB; CREB-1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CREB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 1385). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC008051, NM_004379, NM_134442, NM_001320793, NR_135473, NM_134442.1, NM_134442.2, NM_134442.3, NM_134442.4, NM_004379.1, NM_004379.2, NM_004379.3, NM_004379.4, BC010636, BC010636.1, BC095407, BC095407.1, NM_134442.5, NM_004379.5
UniProt ID P16220
Summary This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. provided by RefSeq, Mar 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics
Ruso-Julve, Pombero, Pilar-Cuéllar et al
Transl Psychiatry (2019) 9 (1), 306 DOI: 10.1038/s41398-019-0647-7
AI Summary: OriGene contributed pGFP-V-RS-CREB1 shRNA expression vectors and scrambled control vectors, which were used to generate stable CREB1 knockdown cell lines to investigate the molecular regulation of ADAMTS2 expression in this study.
Snippet: lls expressing stable shCREB1 constructs were generated by direct transfection by Lipofectamine LTX with PLUS reagent (Invitrogen) using pGFP-V-RS-CREB1 shRNA expression vectors or scrambled control (Origene, MD, USA). …lls expressing stable shCREB1 constructs were generated by direct transfection by Lipofectamine LTX with PLUS reagent (Invitrogen) using pGFP-V-RS-CREB1 shRNA expression vectors or scrambled control (Origene, MD, USA). …
FigureFigureFigure
Showing 1-1 of 1 papers.
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