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DEPDC5 Human shRNA Plasmid Kit (Locus ID 9681)

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TG313503
DEPDC5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 9681
Synonyms DEP.5; FFEVF; FFEVF1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components DEPDC5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 9681). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001007188, NM_001136029, NM_001242896, NM_001242897, NM_014662, NR_110988, NR_146296, NM_001007188.1, NM_001007188.2, NM_014662.1, NM_014662.2, NM_014662.3, NM_014662.4, NM_001136029.1, NM_001136029.2, NM_001242897.1, NM_001242896.1, BC057797, BC136612, BC144291, BC146766, BM145115, NM_001364318, NM_001364320, NM_001369902, NM_001369903, NR_157126, NR_157128, NM_001363852, NM_001363854, NM_001364319, NM_001369901, NR_157125, NM_001242897.2, NM_001242896.3, NM_001136029.3, NM_014662.5, NM_001007188.3
UniProt ID O75140
Summary This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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