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EXTL3 Human shRNA Plasmid Kit (Locus ID 2137)

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SKU
TG313126
EXTL3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 2137
Synonyms BOTV; EXTL1L; EXTR1; ISDNA; REGR; RPR
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components EXTL3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 2137). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001440, NR_073468, NR_073469, NM_001440.1, NM_001440.2, NM_001440.3, BC006363, BC006363.2, NM_001440.4
UniProt ID O43909
Summary This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. provided by RefSeq, Nov 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor
Acquatella-Tran Van Ba, Marchal, François et al
J. Biol. Chem. (2012) 287 (7), 4726-39 DOI: 10.1074/jbc.M111.260349
AI Summary: OriGene’s pGFP-V-RS vector (TG313126) was used to deliver shRNA targeting human EXTL3, enabling the researchers to assess the role of EXTL3 in Reg-1α-induced neurite outgrowth.
Snippet: Cells were spun down at 900 rpm for 5 min and resuspended in 100 µl Nucleofector solution V (Amaxa Biosystems) at room ... ShRNA against human EXTL3 and scrambled, non-effective shRNA (negative control) were cloned in pGFP-V-RS (TG313126, OriGene Technologies
Showing 1-2 of 2 papers.
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