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MYD88 Human shRNA Plasmid Kit (Locus ID 4615)

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TG311320
MYD88 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 4615
Synonyms IMD68; MYD88D
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components MYD88 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 4615). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001172566, NM_001172567, NM_001172568, NM_001172569, NM_002468, NM_002468.2, NM_002468.3, NM_002468.4, NM_001172566.1, NM_001172569.1, NM_001172568.1, NM_001172567.1, BC013589, BC013589.1, NM_001365877, NM_001365876, NM_002468.5
UniProt ID Q99836
Summary This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. provided by RefSeq, Feb 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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