REA (PHB2) Human shRNA Plasmid Kit (Locus ID 11331)

SKU
TG310466
PHB2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 11331
Synonyms BAP; Bap37; BCAP37; hBAP; p22; PNAS-141; REA
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components PHB2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 11331). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001144831, NM_001267700, NM_007273, NM_001144831.1, NM_001267700.1, NM_007273.3, BC110322, BC110322.1, BC013228, BC014766, NM_001144831.2
UniProt ID Q99623
Summary Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1-phosphate (SPP) modulates its regulator activity (PubMed:20959514).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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