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PP2A-alpha (PPP2CA) Human shRNA Plasmid Kit (Locus ID 5515)

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SKU
TG310229
PPP2CA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 5515
Synonyms NEDLBA; PP2Ac; PP2CA; PP2Calpha; RP-C
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PPP2CA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5515). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_002715, NM_001355019, NR_149151, NM_002715.1, NM_002715.2, BC002657, BC002657.2, BC000400, BC019275, BC031696, BM786995, NM_002715.4
UniProt ID P67775
Summary This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model
Bhardwaj, Singh, Srivastava et al
Br. J. Cancer (2014)
Cited by 56
AI Summary: OriGene products, including the PPP2CA-shRNA-pGFP-V-RS plasmid, NT-shRNA-pGFP-V-RS control plasmid, PPP2CA-pCMV6 overexpression construct, and pCMV6 empty vector, were used to manipulate PPP2CA expression in prostate cancer cells, enabling the study of its role in tumor growth, metastasis, and epithelial-to-mesenchymal transition.
Snippet: PPP2CA-short hairpin RNA expression plasmid (PPP2CA-shRNA-pGFP-V-RS), non-targeted control plasmid (NT-shRNA-pGFP-V-RS), PPP2CA overexpression (PPP2CA-pCMV6) and empty vector (pCMV6) constructs were purchased from Origene (Rockville, MD ... Cite SaveSaving
Showing 1-1 of 1 papers.
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