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PTPRB Human shRNA Plasmid Kit (Locus ID 5787)

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SKU
TG310055
PTPRB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 5787
Synonyms HPTP-BETA; HPTPB; PTPB; R-PTP-BETA; VEPTP
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PTPRB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5787). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001109754, NM_001206971, NM_001206972, NM_001330204, NM_002837, NM_002837.1, NM_002837.2, NM_002837.3, NM_002837.4, NM_002837.5, NM_001109754.1, NM_001109754.2, NM_001109754.3, NM_001206971.1, NM_001206971.2, NM_001206972.1, NM_001206972.2, BC043182, BC051329, BC101679, BC113463, BC143356, BC143360, NM_001109754.4
UniProt ID P23467
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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