RBM5 Human shRNA Plasmid Kit (Locus ID 10181)
Specifications
| Product Data | |
| Locus ID | 10181 |
|---|---|
| Synonyms | G15; H37; LUCA-15; LUCA15; RMB5 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RBM5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 10181). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_005778, NR_036627, NM_005778.1, NM_005778.2, NM_005778.3, BC002957, BC156348, BC157102, BM985111 |
| UniProt ID | P52756 |
| Summary | This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. provided by RefSeq, Oct 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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