SERPINB6 Human shRNA Plasmid Kit (Locus ID 5269)
Specifications
| Product Data | |
| Locus ID | 5269 |
|---|---|
| Synonyms | CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SERPINB6 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 5269). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001195291, NM_001271822, NM_001271823, NM_001271824, NM_001271825, NM_001297699, NM_001297700, NM_004568, NM_004568.1, NM_004568.2, NM_004568.3, NM_004568.4, NM_004568.5, NM_001271824.1, NM_001271825.1, NM_001195291.1, NM_001195291.2, NM_001271822.1, NM_001271823.1, NM_001297699.1, NM_001297700.1, BC001394, BC001394.2, BC098564, BM789272, NM_001271823.2, NM_001271822.2, NM_001195291.3, NM_001271824.2, NM_001271825.2, NM_004568.6 |
| UniProt ID | P35237 |
| Summary | The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Sep 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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