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RICTOR Human shRNA Plasmid Kit (Locus ID 253260)

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SKU
TG307650
RICTOR - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 253260
Synonyms AVO3; hAVO3; PIA
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RICTOR - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 253260). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001285439, NM_001285440, NM_152756, NM_152756.1, NM_152756.2, NM_152756.3, NM_152756.4, NM_001285440.1, NM_001285439.1, BC029608, BC051729, BC137163, BC137164, BC144509
UniProt ID Q6R327
Summary RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 PubMed 15268862).supplied by OMIM, Mar 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

mTORC2-Nav1.2 signaling drives early hyperexcitability in Alzheimer's disease mouse model
Dvorak, Noebels
Channels (Austin) (2026) 20 (1), 2687246 DOI: 10.1080/19336950.2026.2687246
AI Summary: OriGene products, specifically the Rictor shRNA construct with GFP reporter (catalog number TG307650) and a control shRNA with GFP reporter, were used in this study to selectively knock down Rictor expression and investigate the role of mTORC2 signaling in neuronal hyperexcitability in an Alzheimer's disease mouse model.
Snippet: and has a GFP reporter was purchased from OriGene (Rockville, MD, USA;catalog and has a GFP reporter was purchased from Origene (Catalog number TL320498), as;ercially available and previously validated [43] short hairpin that selectively and efficiently knocks down Rictor and has a GFP reporter was purchased from OriGene (Rockville, MD, USA;catalog number TG307650), as well as a control short hairpin with a GFP reporter. To knockdown PTEN, a commercially available and previously validated [;- and has a GFP reporter was purchased from OriGene (Rockville, MD, USA
FigureFigureFigure
Potential role of mTORC2 as a therapeutic target in clear cell carcinoma of the ovary
Hisamatsu, Mabuchi, Matsumoto et al
Mol. Cancer Ther. (2013) 12 (7), 1367-77 DOI: 10.1158/1535-7163.MCT-12-1185
AI Summary: In this study, OriGene’s shRNA targeting Rictor (catalog #TG307650) and a nontargeting control shRNA (catalog #TR30013) were used to investigate the role of mTORC2 signaling in ovarian clear cell carcinoma cells.
Snippet: (catalog #sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA). The shRNA specifically targeting Rictor (catalog #TG307650) and a nontargeting control shRNA (catalog #TR30013) were purchased from Origene (Rockville, MD). RMG2 and HAC2 cells
Showing 1-2 of 2 papers.
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