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BIN1 Human shRNA Plasmid Kit (Locus ID 274)

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SKU
TG306398
BIN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 274
Synonyms AMPH2; AMPHL; CNM2; SH3P9
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components BIN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 274). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_004305, NM_139343, NM_139344, NM_139345, NM_139346, NM_139347, NM_139348, NM_139349, NM_139350, NM_139351, NM_001320632, NM_001320633, NM_001320634, NM_001320640, NM_001320641, NM_001320642, NM_139350.1, NM_139350.2, NM_139348.1, NM_139348.2, NM_139343.1, NM_139343.2, NM_139346.2, NM_139349.1, NM_139349.2, NM_139345.1, NM_139345.2, NM_139344.1, NM_139344.2, NM_004305.1, NM_004305.3, NM_139347.1, NM_139347.2, NM_139351.1, NM_139351.2, BC004101, BM711160, BM742027, BM805510, NM_139346.3, NM_139351.3, NM_139347.3, NM_004305.4, NM_139348.3, NM_139349.3, NM_139345.3, NM_139344.3, NM_139350.3, NM_139343.3
UniProt ID O00499
Summary This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. provided by RefSeq, Mar 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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