BIN1 Human shRNA Plasmid Kit (Locus ID 274)
SKU
TG306398
BIN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 274 |
|---|---|
| Synonyms | AMPH2; AMPHL; CNM2; SH3P9 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Format | Retroviral plasmids |
| Components | BIN1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 274). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_004305, NM_139343, NM_139344, NM_139345, NM_139346, NM_139347, NM_139348, NM_139349, NM_139350, NM_139351, NM_001320632, NM_001320633, NM_001320634, NM_001320640, NM_001320641, NM_001320642, NM_139350.1, NM_139350.2, NM_139348.1, NM_139348.2, NM_139343.1, NM_139343.2, NM_139346.2, NM_139349.1, NM_139349.2, NM_139345.1, NM_139345.2, NM_139344.1, NM_139344.2, NM_004305.1, NM_004305.3, NM_139347.1, NM_139347.2, NM_139351.1, NM_139351.2, BC004101, BM711160, BM742027, BM805510, NM_139346.3, NM_139351.3, NM_139347.3, NM_004305.4, NM_139348.3, NM_139349.3, NM_139345.3, NM_139344.3, NM_139350.3, NM_139343.3 |
| UniProt ID | O00499 |
| Summary | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. provided by RefSeq, Mar 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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