HTRA2 Human shRNA Plasmid Kit (Locus ID 27429)

SKU TG304013

HTRA2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 27429
• Synonyms: MGCA8; OMI; PARK13; PRSS25
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: HTRA2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 27429). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_013247, NM_145074, NM_001321727, NM_001321728, NR_135769, NR_135770, NR_135771, NR_135772, NM_013247.1, NM_013247.2, NM_013247.3, NM_013247.4, NM_145074.1, NM_145074.2, BC000096, NM_013247.5
• UniProt ID: O43464
• Summary: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient