KRAS Human shRNA Plasmid Kit (Locus ID 3845)

SKU
TG303636
KRAS - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 3845
Synonyms C-K-RAS; c-Ki-ras2; CFC2; K-Ras; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RASK2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components KRAS - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 3845). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_004985, NM_033360, NM_004985.1, NM_004985.2, NM_004985.3, NM_004985.4, NM_033360.1, NM_033360.2, BC013572, BC013572.2, BC010502, BC029545, NM_001369786, NM_001369787, NM_033360.4, NM_004985.5
UniProt ID P01116
Summary This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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