MAGI3 Human shRNA Plasmid Kit (Locus ID 260425)
Specifications
| Product Data | |
| Locus ID | 260425 |
|---|---|
| Synonyms | dJ730K3.2; MAGI-3 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MAGI3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 260425). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001142782, NM_020965, NM_152900, NM_152900.1, NM_152900.2, NM_001142782.1, NM_020965.2, BC130409, BC144144, NM_152900.3, NM_001142782.2 |
| UniProt ID | Q5TCQ9 |
| Summary | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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