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NOX3 Human shRNA Plasmid Kit (Locus ID 50508)

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SKU
TG302912
NOX3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "NOX3 or NM_015718"

Specifications
Specifications
Product Data
Locus ID 50508
Synonyms GP91-3; MOX-2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components NOX3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 50508). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_015718, NM_015718.1, NM_015718.2, BC160172
UniProt ID Q9HBY0
Summary This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.provided by RefSeq, May 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Targeting tyrosine kinase inhibitor resistant non-small-cell lung cancer by inducing EGFR degradation via methionine 790 oxidation
Leung, Fan, Wong et al
Antioxid. Redox Signal. (2015)
Cited by 80
AI Summary: OriGene products—NOX3 siRNA (cat. no. TG302912) and MsrA siRNA (cat. no. SR302974)—were used to specifically knock down NOX3 and MsrA genes, enabling the study of their roles in redox regulation and EGFR degradation in TKI-resistant NSCLC cells.
Snippet: …The siRNA of NOX3 and MsrA were from Origene, and the cat. … are TG302912 and SR302974, respectively. …
Showing 1-1 of 1 papers.
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