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PDCD4 Human shRNA Plasmid Kit (Locus ID 27250)

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SKU
TG302573
PDCD4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 27250
Synonyms H731
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PDCD4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 27250). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001199492, NM_014456, NM_145341, NM_014456.1, NM_014456.2, NM_014456.3, NM_145341.1, NM_145341.2, NM_145341.3, NM_001199492.1, BC026104, BC015036, BC031049, NM_014456.5
UniProt ID Q53EL6
Summary This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

Expression of TRPM8 in human reactive lymphoid tissues and mature B-cell neoplasms
Hirai, Aung, Ohe et al
Oncol Lett (2018) 16 (5), 5930-5938 DOI: 10.3892/ol.2018.9386
AI Summary: OriGene products contributed to this study by providing the primer pairs used for RT-PCR analysis of TRPM8 mRNA expression in lymphoid tissues and B-cell neoplasms.
Snippet: We used primer pairs designed by OriGene Technologies (Rockville, MD, USA) and produced by Fasmac (Atsugi, Japan);primer sequences were as follows: Sense, 5′-CTGGTTGCGAACTTCCGAAGAG-3′ and antisense, 5′-GGTGCCGAGTAATAGGAGACAC
FigureFigureFigure
Euxanthone Impairs the Metastatic Potential of Osteosarcoma by Reducing COX-2 Expression
Chen, Deng, Zhou et al
Anat Rec (Hoboken) (2018)
AI Summary: In this study, OriGene's PDCD4 Knockdown ShRNAs were used to specifically reduce PDCD4 expression in osteosarcoma cells, helping to elucidate the role of the miR-21/PDCD4/c-jun signaling pathway in the anti-metastatic effects of euxanthone.
Snippet: G418. Quantitative RT-PCR and western blot analysis were utilized to confirm the overexpression of COX-2. PDCD4 Knockdown ShRNAs targeting PDCD4 were purchased from OriGene (Rockville, MD, USA). OS cells were
MicroRNA-429 sensitizes pancreatic cancer cells to gemcitabine through regulation of PDCD4
Yu, Jia, Cheng et al
Am J Transl Res (2017) 9 (11), 5048-5055
AI Summary: OriGene contributed to this study by providing the human PDCD4 shRNA (catalog number TG302573), which was used to knock down PDCD4 expression and investigate its role in pancreatic cancer cell resistance to gemcitabine.
Snippet: RNA interference. For PDCD4 gene knockdown, a set of human PDCD4 shRNA was purchased from Origene (TG302573, Rockville, MD, USA) to express short hairpin RNA (shRNA) targeting PDCD4 mRNA and shRNA containing scrambled sequence were used as
Showing 1-3 of 3 papers.
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