RHOC Human shRNA Plasmid Kit (Locus ID 389)
Specifications
| Product Data | |
| Locus ID | 389 |
|---|---|
| Synonyms | ARH9; ARHC; H9; RHOH9 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | RHOC - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 389). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_001042678, NM_001042679, NM_175744, NM_001042679.1, NM_001042678.1, NM_005167.2, NM_175744.1, NM_175744.2, NM_175744.3, NM_175744.4, BC009177, BC009177.2, BC052808, BC052808.1, BC007245, NM_175744.5 |
| UniProt ID | P08134 |
| Summary | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Minami, Ueda, Ishimoto et al
Biochem Biophys Res Commun (2020) 532 (3), 427-432 DOI: 10.1016/j.bbrc.2020.08.087
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