RHOC Human shRNA Plasmid Kit (Locus ID 389)

SKU
TG302002
RHOC - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 389
Synonyms ARH9; ARHC; H9; RHOH9
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RHOC - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 389). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_001042678, NM_001042679, NM_175744, NM_001042679.1, NM_001042678.1, NM_005167.2, NM_175744.1, NM_175744.2, NM_175744.3, NM_175744.4, BC009177, BC009177.2, BC052808, BC052808.1, BC007245, NM_175744.5
UniProt ID P08134
Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Cooperation of G12/13 and Gi proteins via lysophosphatidic acid receptor-2 (LPA2) signaling enhances cancer cell survival to cisplatin
Minami, Ueda, Ishimoto et al
Biochem Biophys Res Commun (2020) 532 (3), 427-432 DOI: 10.1016/j.bbrc.2020.08.087
Cited by 14
AI Summary: In this study, OriGene products including LPA2 shRNA (for LPA2 knockdown), RhoA shRNA, and RhoC shRNA (for generating HT1080-RhoA and HT1080-RhoC knockdown cell lines) were used to investigate the roles of LPA2, RhoA, and RhoC in cancer cell survival to cisplatin.
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products