Maged1 Mouse shRNA Plasmid (Locus ID 94275)
Specifications
| Product Data | |
| Locus ID | 94275 |
|---|---|
| Synonyms | 2810433C11Rik; 5430405L04Rik; Dlixin; Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; mFLJ00163; NRAGE |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Maged1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 94275). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC016438, BC031461, NM_019791, NM_019791.1, NM_019791.2, NM_019791.3 |
| UniProt ID | Q9QYH6 |
| Summary | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA coregulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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