Rasa4 Mouse shRNA Plasmid (Locus ID 54153)
Specifications
| Product Data | |
| Locus ID | 54153 |
|---|---|
| Synonyms | AA793972; AW112107; BB079060; CAPRI; GAPL |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Rasa4 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 54153). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC057460, NM_001039103, NM_133914, NM_133914.2, NM_133914.3, NM_001039103.1, NM_001039103.2, NM_001039103.3, BC027230, BC049381, BC092143 |
| UniProt ID | Q6PFQ7 |
| Summary | Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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