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Nckap1 Mouse shRNA Plasmid (Locus ID 50884)

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SKU
TF510899
Nckap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 50884
Synonyms C79304; H19; Hem-2; Hem2; mh19; mKIAA0587; Nap1; p125Nap1
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Nckap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 50884). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001290745, NM_016965, NM_001355410, NM_001355411, NM_016965.1, NM_016965.2, NM_016965.3, NM_001290745.1, BC003962, BC032206, BC054383, BC060197, BC127067, BC148377
UniProt ID P28660
Summary Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

PTEN dephosphorylates Abi1 to promote epithelial morphogenesis
Qi, Liu, Chao et al
J. Cell Biol. (2020) 219 (9) DOI: 10.1083/jcb.201910041
Cited by 19
AI Summary: OriGene's shRNA vectors targeting mouse Abi1, Abi2, and Nckap1 were used to specifically knock down these genes in embryonic stem cells, enabling the authors to investigate their roles in PTEN-mediated epithelial morphogenesis.
Snippet: The shRNA vectors targeting specifically mouse Abi1, Abi2, Nckap1, and the control scrambled sequences were obtained from OriGene. The effective sequences selected by immunoblot analysis of stably transfected ES cell lines are 59-TCAGAGACC AAGGACGCATTAGTGGAAGT-39 (Abi1), 59-ACTGCGAGAATAACT ACATCCAGTCACCA-39 (Abi2), and 59-ACGCCTTGGTCAGATGA TTGTGGACTATG-39 (Nckap1). …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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