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Maff Mouse shRNA Plasmid (Locus ID 17133)

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SKU
TF501290
Maff - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 17133
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Maff - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 17133). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC022952, NM_001304830, NM_001304831, NM_001304832, NM_010755, NM_010755.1, NM_010755.2, NM_010755.3, NM_010755.4
UniProt ID O54791
Summary Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths
Wolock, Krishnan, Tenen et al
Cell Rep (2019) 28 (2), 302-311.e5 DOI: 10.1016/j.celrep.2019.06.031
AI Summary: OriGene products, specifically shRNA constructs targeting Nr4a3 (TF501493), Maff (TF501290), Dlx3 (TF500537), Creb3l3 (TF513785), and Mef2c (TF511428), were used in this study to perform targeted knockdowns of key transcription factors, enabling validation of differentiation pathways in bone marrow stromal cell populations.
Snippet: Osteogenic media STEMCELL Technologies Cat# 05504 Adipogenesis media STEMCELL Technologies Cat# 05503 Chondrocyte differentiation GIBCO Cat# A1007101 shRNA - TF501493 (Nr4a3) Origene Mouse, 4 unique 29-mer shRNA constructs in retroviral RFP vector shRNA-TF501290(Maff) Origene 4 unique shRNA shRNA - TF500537 (Dlx3) Origene 4 unique shRNA shRNA - TF513785;Osteogenic media STEMCELL Technologies Cat# 05504 Adipogenesis media STEMCELL Technologies Cat# 05503 Chondrocyte differentiation GIBCO Cat# A1007101 shRNA – TF501493 (Nr4a3) Origene Mouse, 4 unique 29-mer shRNA constructs in retroviral RFP vector shRNA - TF501290 (Maff) Origene 4 unique shRNA shRNA - TF500537 (Dlx3) Origene 4 unique shRNA shRNA - TF513785 (Creb3l3) Origene 4 unique shRNA shRNA - TF511428 (Mef2c) Origene 4 unique shRNA
Showing 1-1 of 1 papers.
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