Il10 Mouse shRNA Plasmid (Locus ID 16153)

SKU
TF501065
Il10 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 16153
Synonyms CSIF; If2a; IL-; Il-10
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components Il10 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 16153). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC120612, NM_010548, NM_010548.1, NM_010548.2, BC137844
UniProt ID P18893
Summary This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. provided by RefSeq, Sep 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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