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Diaph1 Mouse shRNA Plasmid (Locus ID 13367)

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SKU
TF500527
Diap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
In Control Promo
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 13367
Synonyms D18Wsu154; D18Wsu154e; Di; Dia1; Diap1; Drf; Drf1; mDi; p140m; p140mDia
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Diap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 13367). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC070412, NM_007858, NM_007858.1, NM_007858.2, NM_007858.3, NM_007858.4, BC070412.1, BC012974, BC021396, BC024979, BC029331
UniProt ID O08808
Summary This gene encodes a member of the formin family of proteins that play important roles in cytoskeletal rearragnement by nucleation of actin filaments. Mice lacking the encoded protein develop age-dependent myeloproliferative defects resembling human myeloproliferative syndrome and myelodysplastic syndromes. Trafficking of T lymphocytes to secondary lymphoid organs and egression of thymocytes from the thymus are impaired in these animals. Lack of the encoded protein in T lymphocytes and thymocytes also reduces chemotaxis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.