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Runx1 Mouse shRNA Plasmid (Locus ID 12394)

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SKU
TF500282
Runx1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 12394
Synonyms AML1; CBF-alpha-2; Cbfa2; Pebp2a2; Pebpa2b
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Runx1 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 12394). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC069929, NM_001111021, NM_001111022, NM_001111023, NM_009821, NM_001111022.1, NM_001111022.2, NM_009821.1, NM_009821.2, NM_009821.3, NM_001111021.1, NM_001111021.2, NM_001111023.1, NM_001111023.2
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

Neural EGFL like 1 as a potential pro-chondrogenic, anti-inflammatory dual-functional disease-modifying osteoarthritis drug
Li, Zheng, Ha et al
Biomaterials (2020) 226, 119541 DOI: 10.1016/j.biomaterials.2019.119541
Cited by 63
AI Summary: In this study, OriGene products, including the Human NELL1 cDNA clone and mouse Runx1 (NM_009820) qPCR primer pair, were used to investigate the roles of NELL-1 and RUNX1 in chondrocyte function and osteoarthritis pathogenesis.
FigureFigure
Nfatc1 Is a Functional Transcriptional Factor Mediating Nell-1-Induced Runx3 Upregulation in Chondrocytes
Li, Zheng, Zhang et al
Int J Mol Sci (2018) 19 (1) DOI: 10.3390/ijms19010168
AI Summary: OriGene provided shRNA plasmids targeting mouse Nfatc1 and Runx1, as well as a control shRNA plasmid, which were used to investigate the roles of these genes in Nell-1-induced Runx3 upregulation in chondrocytes.
Snippet: Plasmid packages harboring shRNA targeting mouse Nfatc1 and Runx1, respectively, were obtained from Origene (Rockville, MD, USA). … P2 chondrocytes isolated from Runx2−/− mice were transfected with the shRNA plasmid with Lipofectamine 3000 reagent (Invitrogen). A control shRNA plasmid provided by OriGene was also used to transfect Runx2−/− mouse chondrocytes. …
FigureFigureFigure
RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency
Kaur, Jalagadugula, Mao et al
Blood (2010) 115 (15), 3128-35 DOI: 10.1182/blood-2009-04-214601
Cited by 73
AI Summary: OriGene products contributed to this paper by providing the RUNX1 cDNA clone (RC211491) for overexpression studies and the RUNX1 siRNA (SR304274) for gene knockdown experiments, enabling the authors to investigate RUNX1’s regulatory effect on ALOX12 expression.
Showing 1-3 of 3 papers.
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