Casp8 Mouse shRNA Plasmid (Locus ID 12370)
Specifications
| Product Data | |
| Locus ID | 12370 |
|---|---|
| Synonyms | Casp; CASP-8; FLI; FLICE; MAC; MACH; Mch5 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Casp8 - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 12370). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC006737, BC049955, NM_001080126, NM_001277926, NM_009812, NM_001080126.1, NM_001277926.1, NM_009812.2 |
| UniProt ID | O89110 |
| Summary | This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. provided by RefSeq, Apr 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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