Bik Mouse shRNA Plasmid (Locus ID 12124)
SKU
TF500209
Bik - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 12124 |
|---|---|
| Synonyms | Biklk; Blk; Nbk |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Bik - Mouse, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 12124). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC003732, NM_007546, NM_007546.1, NM_007546.2 |
| UniProt ID | O70337 |
| Summary | Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1 or Bcl-2 suppresses this death-promoting activity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria
Mebratu, Leyva-Baca, Wathelet et al
Nat Commun (2017) 8 (1), 803 DOI: 10.1038/s41467-017-00975-w
Mebratu, Leyva-Baca, Wathelet et al
Nat Commun (2017) 8 (1), 803 DOI: 10.1038/s41467-017-00975-w
AI Summary: OriGene products, specifically the retroviral silencing vectors encoding Bik shRNA, DAPk1, and the control vector, were used to manipulate gene expression and investigate the roles of Bik and DAPk1 in regulating apoptosis and ER-mitochondria interactions in this study.
Snippet: Retroviral silencing vector encoding for Bik shRNA, DAPk1 and the control vector were purchased from Origene (Origene Technologies, Inc)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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