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TNIK Human shRNA Plasmid Kit (Locus ID 23043)

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SKU
TF320665
KIAA0551 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 23043
Synonyms MRT54
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components KIAA0551 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 23043). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001161560, NM_001161561, NM_001161562, NM_001161563, NM_001161564, NM_001161565, NM_001161566, NM_015028, NR_027767, NM_015028.1, NM_015028.2, NM_015028.3, NM_001161566.1, NM_001161566.2, NM_001161565.1, NM_001161565.2, NM_001161564.1, NM_001161564.2, NM_001161563.1, NM_001161563.2, NM_001161562.1, NM_001161562.2, NM_001161561.1, NM_001161561.2, NM_001161560.1, NM_001161560.2, BC018093, BC019081, BC055427, BC150256
UniProt ID Q9UKE5
Summary Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK
Wang, Amato, Rubitski et al
J. Pharmacol. Exp. Ther. (2015)
Cited by 38
AI Summary: OriGene products contributed to this study by providing RFP and Flag-p120-catenin expression plasmids as well as scrambled and TNIK-targeting shRNAs in the pRFP-C-RS vector, which were used to manipulate and analyze TNIK and its substrates in cellular experiments.
Snippet: RFP and Flag-p120-catenin were purchased from Origene. HA-TNIK-T187A and T181A were generated with the Quickchange Lightning kit ... The scrambled and TNIK shRNAs in the pRFP-C-RS vector were purchased from Origene. The shRNA sequences are: ... Cite SaveSaving
Showing 1-1 of 1 papers.
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