TIE1 Human shRNA Plasmid Kit (Locus ID 7075)
Specifications
| Product Data | |
| Locus ID | 7075 |
|---|---|
| Synonyms | JTK14; LMPHM11; TIE |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | TIE1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 7075). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001253357, NM_005424, NM_005424.1, NM_005424.2, NM_005424.3, NM_005424.4, NM_001253357.1, BC038239, BC038239.1, BM970991, NM_001253357.2 |
| UniProt ID | P35590 |
| Summary | This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Nov 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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