RET Human shRNA Plasmid Kit (Locus ID 5979)
SKU
TF320512
RET - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 5979 |
|---|---|
| Synonyms | PTC, MTC1, HSCR1, MEN2A, MEN2B, RET51 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | RET - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 5979). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_000323, NM_020629, NM_020630, NM_020975, NM_001355216, NM_020630.1, NM_020630.2, NM_020630.3, NM_020630.4, NM_020975.2, NM_020975.3, NM_020975.4, NM_000323.2, BC004257, BC004257.1, BC003072, BM661773, BM703293, NM_020975.6 |
| UniProt ID | P07949 |
| Summary | This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. provided by RefSeq, Sep 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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