MATK Human shRNA Plasmid Kit (Locus ID 4145)
Specifications
| Product Data | |
| Locus ID | 4145 |
|---|---|
| Synonyms | CHK; CTK; HHYLTK; HYL; HYLTK; Lsk |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MATK - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 4145). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_002378, NM_139354, NM_139355, NM_139354.1, NM_139354.2, NM_139355.1, NM_139355.2, NM_002378.1, NM_002378.2, NM_002378.3, BC000114, BC000114.1, BC003109, BM925586, NM_002378.4, NM_139355.3 |
| UniProt ID | P42679 |
| Summary | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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