Eph receptor B2 (EPHB2) Human shRNA Plasmid Kit (Locus ID 2048)
Specifications
| Product Data | |
| Locus ID | 2048 |
|---|---|
| Synonyms | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | EPHB2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 2048). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001309192, NM_001309193, NM_004442, NM_017449, NM_017449.1, NM_017449.2, NM_017449.3, NM_017449.4, NM_004442.2, NM_004442.3, NM_004442.4, NM_004442.5, NM_004442.6, NM_004442.7, BC007903, BC018763, BC041017, BC067861, BC146296 |
| UniProt ID | P29323 |
| Summary | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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