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CLK2 Human shRNA Plasmid Kit (Locus ID 1196)

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SKU
TF320305
CLK2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 1196
Synonyms CDC-like kinase 2; CLK kinase; dual specificity protein kinase CLK2; hCLK2; hCLK2, MGC61500; MGC61500
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CLK2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 1196). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001291, NM_001294338, NM_001294339, NM_003993, NM_003993.1, NM_003993.2, NM_003993.3, NM_001294339.1, NM_001294338.1, NM_001291.2, BC053603, BC006274, BC014067, NM_001363704, NM_001294338.2, NM_001294339.2
UniProt ID P49760
Summary This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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