CLK2 Human shRNA Plasmid Kit (Locus ID 1196)
SKU
TF320305
CLK2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1196 |
|---|---|
| Synonyms | CDC-like kinase 2; CLK kinase; dual specificity protein kinase CLK2; hCLK2; hCLK2, MGC61500; MGC61500 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | CLK2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 1196). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001291, NM_001294338, NM_001294339, NM_003993, NM_003993.1, NM_003993.2, NM_003993.3, NM_001294339.1, NM_001294338.1, NM_001291.2, BC053603, BC006274, BC014067, NM_001363704, NM_001294338.2, NM_001294339.2 |
| UniProt ID | P49760 |
| Summary | This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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