BTK Human shRNA Plasmid Kit (Locus ID 695)
Specifications
| Product Data | |
| Locus ID | 695 |
|---|---|
| Synonyms | AGMX1; AT; ATK; BPK; IGHD3; IMD1; PSCTK1; XLA |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BTK - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 695). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_000061, NM_001287344, NM_001287345, NM_000061.1, NM_000061.2, NM_001287345.1, NM_001287344.1, BC109079, BC109080, NM_000061.3 |
| UniProt ID | Q06187 |
| Summary | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Dec 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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