ERK5 (MAPK7) Human shRNA Plasmid Kit (Locus ID 5598)
Specifications
| Product Data | |
| Locus ID | 5598 |
|---|---|
| Synonyms | BMK1; ERK4; ERK5; PRKM7 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MAPK7 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 5598). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_002749, NM_139032, NM_139033, NM_139034, NM_139032.1, NM_139032.2, NM_002749.1, NM_002749.2, NM_002749.3, NM_139034.1, NM_139034.2, NM_139033.1, NM_139033.2, BC007404, BC007404.2, BC009963, BC009963.2, BC030134, BC007992, NM_002749.4, NM_139034.3, NM_139032.3 |
| UniProt ID | Q13164 |
| Summary | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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