B7H3 (CD276) Human shRNA Plasmid Kit (Locus ID 80381)
Specifications
| Product Data | |
| Locus ID | 80381 |
|---|---|
| Synonyms | 4Ig-B7-H3; B7-H3; B7H3; B7RP-2 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CD276 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 80381). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC011578, NM_001024736, NM_025240, NM_001329628, NM_001329629, NM_001024736.1, NM_025240.1, NM_025240.2, BC062581, NM_001024736.2 |
| UniProt ID | Q5ZPR3 |
| Summary | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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