PDE6D Human shRNA Plasmid Kit (Locus ID 5147)
Specifications
| Product Data | |
| Locus ID | 5147 |
|---|---|
| Synonyms | JBTS22; PDED |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PDE6D - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 5147). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001291018, NM_002601, NR_110994, NM_002601.1, NM_002601.2, NM_002601.3, NM_001291018.1, BC007831, BC001054, BC017467, NM_002601.4 |
| UniProt ID | O43924 |
| Summary | This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. provided by RefSeq, Mar 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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