ASAH1 Human shRNA Plasmid Kit (Locus ID 427)
Specifications
| Product Data | |
| Locus ID | 427 |
|---|---|
| Synonyms | AC; ACDase; ASAH; PHP; PHP32; SMAPME |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ASAH1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 427). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001127505, NM_004315, NM_177924, NM_177924.1, NM_177924.2, NM_177924.3, NM_177924.4, NM_004315.1, NM_004315.2, NM_004315.3, NM_004315.4, NM_004315.5, NM_001127505.1, NM_001127505.2, BC016481, BC016828, BC035453, NM_001363743, NM_001127505.3 |
| UniProt ID | Q13510 |
| Summary | This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. provided by RefSeq, Oct 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.