ASAH1 Human shRNA Plasmid Kit (Locus ID 427)

SKU
TF314638
ASAH1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 427
Synonyms AC; ACDase; ASAH; PHP; PHP32; SMAPME
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ASAH1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 427). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001127505, NM_004315, NM_177924, NM_177924.1, NM_177924.2, NM_177924.3, NM_177924.4, NM_004315.1, NM_004315.2, NM_004315.3, NM_004315.4, NM_004315.5, NM_001127505.1, NM_001127505.2, BC016481, BC016828, BC035453, NM_001363743, NM_001127505.3
UniProt ID Q13510
Summary This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. provided by RefSeq, Oct 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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