GCN2 (EIF2AK4) Human shRNA Plasmid Kit (Locus ID 440275)

SKU
TF313266
EIF2AK4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 440275
Synonyms GCN2; PVOD2
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components EIF2AK4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 440275). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001013703, NM_001013703.1, NM_001013703.2, NM_001013703.3, BC009350, BC014915, BC019914, BC061591, BC078179, BC146319
UniProt ID Q9P2K8
Summary This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. provided by RefSeq, Mar 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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