PDGF Receptor alpha (PDGFRA) Human shRNA Plasmid Kit (Locus ID 5156)
Specifications
| Product Data | |
| Locus ID | 5156 |
|---|---|
| Synonyms | CD140A; PDGFR-2; PDGFR2 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PDGFRA - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 5156). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_006206, NM_001347827, NM_001347828, NM_001347829, NM_001347830, NM_006206.1, NM_006206.2, NM_006206.3, NM_006206.4, NM_006206.5, BC015186, BC063414 |
| UniProt ID | P16234 |
| Summary | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. provided by RefSeq, Mar 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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