TREM2 (NM_018965) Human Recombinant Protein

SKU TP762671

Purified recombinant protein of Human triggering receptor expressed on myeloid cells 2 (TREM2), 19His-174Ser, with N-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(19His-174Ser) of TREM2
• Tag: N-His
• Predicted MW: 17.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_061838
• Locus ID: 54209
• UniProt ID: Q9NZC2 Q5TCX1
• Cytogenetics: 6p21.1
• RefSeq Size: 1041
• RefSeq ORF: 690
• Synonyms: PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
• Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane