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C2 (NM_000063) Human Recombinant Protein

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SKU
TP762664
Purified recombinant protein of Human complement component 2 (C2), transcript variant 1, full length, with N-GST and C-His tag, expressed in E.coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region full length of C2
Tag N-GST and C-HIS
Predicted MW 111.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000054
Locus ID 717
UniProt ID P06681 Q5JP69 Q53HP3
Cytogenetics 6p21.33
RefSeq Size 2862
RefSeq ORF 2256
Synonyms ARMD14; CO2
Summary Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.provided by RefSeq, Mar 2009
Protein Categories Allergies and autoimmune diseases, Enzyme: Peptidases, Intracellular Proteins, Nervous system Diseases, Secreated Proteins
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades, Systemic lupus erythematosus
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Other "C2" proteins (5)
SKU Description Size Price
LC400024 Lyophilized C2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC429041 Lyophilized C2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400024 Transient overexpression lysate of complement component 2 (C2), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY429041 Transient overexpression lysate of complement component 2 (C2), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP762175 Purified recombinant protein of Human complement component 2 (C2), transcript variant 1, Ser469-End, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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